Trefoil is a biotechnology company that brings forward novel engineered FGF-1 compounds to treat endothelial cell mediated diseases. Founded by David Eveleth, Kenneth Thomas, Michael Blaber, and Ralph Bradshaw in 2014, Trefoil Therapeutics is backed by National Institutes of Health, Hatteras Venture Partners, Correlation Ventures, Solasta Ventures, and Bios Partners and is headquartered in San Diego.